Fractionation of a phenolic compound from water spinach (Ipomoea aquatica) herbs as anti-dandruff against Malassezia sp.

 Dandruff is a scalp disorder caused by fungus ( Malassezia sp. ). Water spinach Ipomoea aquatica ) contains phenolic compounds which has antifungal activity. The purpose of this research to know the active fraction herb antidandruff activity against study used true experimental design test. Fractionation column chromatography stationary phase with silica gel 60 powder and mobile chloroform/methanol/acetyl acetate (8/2/0,1 v/v/v). In vitro based on minimum inhibitory consentration (MIC) (MFC) human dandruff isolate. average MIC MFC among groups compared Friedman test (p≤ 0,05). 7 water have (MIC 125 µg/mL 250 µg/mL). Based results, identified as compound.